diff --git a/Makefile b/Makefile
index 2a69708d1..e32a6a368 100644
--- a/Makefile
+++ b/Makefile
@@ -123,8 +123,8 @@ ifneq ($(shell :; command -v brew),)
 BREW_PREFIX := $(shell brew --prefix)/opt
 $(info $$BREW_PREFIX is [${BREW_PREFIX}])
 ifeq ($(ENABLE_PYOSYS),1)
-CXXFLAGS += -I$(BREW_PREFIX)/boost/include/boost
-LINKFLAGS += -L$(BREW_PREFIX)/boost/lib
+CXXFLAGS += -I$(BREW_PREFIX)/boost/include
+LINKFLAGS += -L$(BREW_PREFIX)/boost/lib -L$(BREW_PREFIX)/boost-python3/lib
 endif
 CXXFLAGS += -I$(BREW_PREFIX)/readline/include
 LINKFLAGS += -L$(BREW_PREFIX)/readline/lib
@@ -330,8 +330,13 @@ TARGETS += libyosys.so
 endif
 
 ifeq ($(ENABLE_PYOSYS),1)
+# python-config --ldflags includes -l and -L, but LINKFLAGS is only -L
+LINKFLAGS += $(filter-out -l%,$(shell $(PYTHON_CONFIG) --ldflags))
+LIBS += $(shell $(PYTHON_CONFIG) --libs)
+CXXFLAGS += $(shell $(PYTHON_CONFIG) --includes) -DWITH_PYTHON
+
 # Detect name of boost_python library. Some distros use boost_python-py<version>, other boost_python<version>, some only use the major version number, some a concatenation of major and minor version numbers
-CHECK_BOOST_PYTHON = (echo "int main(int argc, char ** argv) {return 0;}" | $(CXX) -xc -o /dev/null $(shell $(PYTHON_CONFIG) --ldflags) -l$(1) - > /dev/null 2>&1 && echo "-l$(1)")
+CHECK_BOOST_PYTHON = (echo "int main(int argc, char ** argv) {return 0;}" | $(CXX) -xc -o /dev/null $(LINKFLAGS) $(LIBS) -l$(1) - > /dev/null 2>&1 && echo "-l$(1)")
 BOOST_PYTHON_LIB ?= $(shell \
 	$(call CHECK_BOOST_PYTHON,boost_python-py$(subst .,,$(PYTHON_VERSION))) || \
 	$(call CHECK_BOOST_PYTHON,boost_python-py$(PYTHON_MAJOR_VERSION)) || \
@@ -343,11 +348,7 @@ ifeq ($(BOOST_PYTHON_LIB),)
 $(error BOOST_PYTHON_LIB could not be detected. Please define manually)
 endif
 
-LIBS += $(shell $(PYTHON_CONFIG) --libs) $(BOOST_PYTHON_LIB) -lboost_system -lboost_filesystem
-# python-config --ldflags includes LIBS for some reason
-LINKFLAGS += $(filter-out -l%,$(shell $(PYTHON_CONFIG) --ldflags))
-CXXFLAGS += $(shell $(PYTHON_CONFIG) --includes) -DWITH_PYTHON
-
+LIBS += $(BOOST_PYTHON_LIB) -lboost_system -lboost_filesystem
 PY_WRAPPER_FILE = kernel/python_wrappers
 OBJS += $(PY_WRAPPER_FILE).o
 PY_GEN_SCRIPT= py_wrap_generator